hrp0097fc5.4 | Diabetes and insulin 1 | ESPE2023

Changes of intestinal flora in children with type 1 diabetes mellitus and its related immune mechanism

Liu Ying , Li Liman , Wu Jin , Li Hong

Key words: Type 1 diabetes mellitus; Intestinal flora; metagenomic sequencing; cytokines; AutoimmunityObjective: This study aims to verify the effect of intestinal microbiota diversity on the disease development of T1DM mice model, and to explore the mechanism of intestinal microbiota in the development of type 1 diabetes mediated by related cytokines.Method: T1DM mouse model was e...